Unbalance Between Apoptosis and Proliferation in Female Genital Tract Malignancies

Deregulated Apoptosis in Female Genital Tract Cancer

Apoptosis is initiated via the mitochondrial or the death receptor pathway. Central to the mitochondrial pathway is the release of cytochrome c from the mitochondria, leading to activation of the caspase cascade and execution of apoptosis.1 The mitochondrial pathway is regulated by the BCL-2 family of proteins, i.e. proapoptotic BAX and BAK as well as antiapoptotic BCL-2 and BCL-xL. The death r...

Female Genital Tract Tumors

Female Genital Tract Cysts

Cystic diseases in the female pelvis are common. Cysts of the female genital tract comprise a large number of physiologic and pathologic cysts. The majority of cystic pelvic masses originate in the ovary, and they can range from simple, functional cysts to malignant ovarian tumors. Non-ovarian cysts of female genital system are appeared at least as often as ovarian cysts. In this review, we aim...

Genital tract malignancies in postmenopausal women.

BACKGROUND The most common malignancy in women is breast carcinoma. The next common cancer is genital tract malignancies which constitute 14% of cancers in women. Objective of this study was to determine the type and frequency of genital tract malignancy in postmenopausal women and to find the age distribution of genital tract malignancies. METHODS This descriptive cross sectional study was c...

Chlamydia A in the female genital tract.

The first genital tract isolates of Chlamydia A were obtained from parents of babies suffering from TRIC ophthalmia neonatorum, by growth in the yolk sac of fertile eggs 1964). It was noted that the fathers of these babies were frequently suffering from non-gonococcal urethritis (NGU) and that the mothers often showed changes in the cervix. The isolation of Chlamydia from two of nine un-selecte...